Please use this identifier to cite or link to this item: https://repositorio.uca.edu.ar/handle/123456789/9552
Título : Chronobiological theories of mood disorder
Autor : Zaki, Nevin F. W. 
Spence, David Warren 
BaHammam, Ahmed S. 
Pandi Perumal, Seithikurippu R. 
Cardinali, Daniel Pedro 
Brown, Gregory M. 
Palabras clave : LUZCRONOBIOLOGIARITMO CIRCADIANODEPRESIONMELATONINATRASTORNOS DEL ESTADO DE ANIMO
Fecha de publicación : 2018
Editorial : Springer
Cita : Zaki, N.F. et al. Chronobiological theories of mood disorder [en línea]. European Archives of Psychiatry and Clinical Neuroscience. 2018, 268(2). doi:10.1007/s00406-017-0835-5 Disponible en: https://repositorio.uca.edu.ar/handle/123456789/9552
Resumen : Abstract: Major depressive disorder (MDD) remains the most prevalent mental disorder and a leading cause of disability, affecting approximately 100 million adults worldwide. The disorder is characterized by a constellation of symptoms affecting mood, anxiety, neurochemical balance, sleep patterns, and circadian and/or seasonal rhythm entrainment. However, the mechanisms underlying the association between chronobiological parameters and depression remain unknown. A PubMed search was conducted to review articles from 1979 to the present, using the following search terms: "chronobiology," "mood," "sleep," and "circadian rhythms." We aimed to synthesize the literature investigating chronobiological theories of mood disorders. Current treatments primarily include tricyclic antidepressants and selective serotonin reuptake inhibitors, which are known to increase extracellular concentrations of monoamine neurotransmitters. However, these antidepressants do not treat the sleep disturbances or circadian and/or seasonal rhythm dysfunctions associated with depressive disorders. Several theories associating sleep and circadian rhythm disturbances with depression have been proposed. Current evidence supports the existence of associations between these, but the direction of causality remains elusive. Given the existence of chronobiological disturbances in depression and evidence regarding their treatment in improving depression, a chronobiological approach, including timely use of light and melatonin agonists, could complement the treatment of MDD.
URI : https://repositorio.uca.edu.ar/handle/123456789/9552
ISSN : 0940-1334 (impreso)
1433-8491 (online)
Disciplina: MEDICINA
DOI: 10.1007/s00406-017-0835-5
Derechos: Acceso abierto
Appears in Collections:Artículos

Files in This Item:
File Description SizeFormat
chronobiological-theories-mood-disorder.pdf242,07 kBAdobe PDFThumbnail
View/Open
Show full item record

Page view(s)

64
checked on Mar 3, 2021

Download(s)

285
checked on Mar 3, 2021

Google ScholarTM

Check


Altmetric


This item is licensed under a Creative Commons License Creative Commons