Please use this identifier to cite or link to this item: https://repositorio.uca.edu.ar/handle/123456789/9552
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dc.contributor.authorZaki, Nevin F. W.es
dc.contributor.authorSpence, David Warrenes
dc.contributor.authorBaHammam, Ahmed S.es
dc.contributor.authorPandi Perumal, Seithikurippu R.es
dc.contributor.authorCardinali, Daniel Pedroes
dc.contributor.authorBrown, Gregory M.es
dc.date.accessioned2020-03-13T22:11:54Z-
dc.date.available2020-03-13T22:11:54Z-
dc.date.issued2018-
dc.identifier.citationZaki, N.F. et al. Chronobiological theories of mood disorder [en línea]. European Archives of Psychiatry and Clinical Neuroscience. 2018, 268(2). doi:10.1007/s00406-017-0835-5 Disponible en: https://repositorio.uca.edu.ar/handle/123456789/9552es
dc.identifier.issn0940-1334 (impreso)-
dc.identifier.issn1433-8491 (online)-
dc.identifier.urihttps://repositorio.uca.edu.ar/handle/123456789/9552-
dc.description.abstractAbstract: Major depressive disorder (MDD) remains the most prevalent mental disorder and a leading cause of disability, affecting approximately 100 million adults worldwide. The disorder is characterized by a constellation of symptoms affecting mood, anxiety, neurochemical balance, sleep patterns, and circadian and/or seasonal rhythm entrainment. However, the mechanisms underlying the association between chronobiological parameters and depression remain unknown. A PubMed search was conducted to review articles from 1979 to the present, using the following search terms: "chronobiology," "mood," "sleep," and "circadian rhythms." We aimed to synthesize the literature investigating chronobiological theories of mood disorders. Current treatments primarily include tricyclic antidepressants and selective serotonin reuptake inhibitors, which are known to increase extracellular concentrations of monoamine neurotransmitters. However, these antidepressants do not treat the sleep disturbances or circadian and/or seasonal rhythm dysfunctions associated with depressive disorders. Several theories associating sleep and circadian rhythm disturbances with depression have been proposed. Current evidence supports the existence of associations between these, but the direction of causality remains elusive. Given the existence of chronobiological disturbances in depression and evidence regarding their treatment in improving depression, a chronobiological approach, including timely use of light and melatonin agonists, could complement the treatment of MDD.es
dc.formatapplication/pdfes
dc.language.isoenges
dc.publisherSpringeres
dc.rightsAcceso abierto*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/*
dc.sourceEuropean Archives of Psychiatry and Clinical Neuroscience. 2018, 268(2)es
dc.subjectLUZes
dc.subjectCRONOBIOLOGIAes
dc.subjectRITMO CIRCADIANOes
dc.subjectDEPRESIONes
dc.subjectMELATONINAes
dc.subjectTRASTORNOS DEL ESTADO DE ANIMOes
dc.titleChronobiological theories of mood disorderes
dc.typeArtículoes
dc.identifier.doi10.1007/s00406-017-0835-5-
dc.identifier.pmid28894915-
uca.disciplinaMEDICINAes
uca.issnrd1es
uca.affiliationFil: Zaki, Nevin F. W. Mansoura University. Faculty of Medicine. Department of Psychiatry; Egiptoes
uca.affiliationFil: Spence, David Warren. Investigador independiente; Canadáes
uca.affiliationFil: BaHammam, Ahmed S. King Saud University. College of Medicine. University Sleep Disorders Center; Arabia Sauditaes
uca.affiliationFil: Pandi Perumal, Seithikurippu R. Somnogen Inc; Estados Unidoses
uca.affiliationFil: Cardinali, Daniel Pedro. Pontificia Universidad Católica Argentina. Facultad de Ciencias Médicas. Instituto de Investigaciones Biomédicas; Argentinaes
uca.affiliationFil: Cardinali, Daniel Pedro. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentinaes
uca.affiliationFil: Cardinali, Daniel Pedro. Pontificia Universidad Católica Argentina. Facultad de Ciencias Médicas. Departamento de Docencia e Investigación; Argentinaes
uca.affiliationFil: Brown, Gregory M. University of Toronto. Department of Psychiatry. Centre for Addiction and Mental Health; Canadáes
uca.versionacceptedVersiones
item.languageiso639-1en-
item.grantfulltextopen-
item.fulltextWith Fulltext-
crisitem.author.deptConsejo Nacional de Investigaciones Científicas y Técnicas-
crisitem.author.deptInstituto de Investigaciones Biomédicas - BIOMED-
crisitem.author.orcid0000-0002-0813-9088-
crisitem.author.parentorgFacultad de Ciencias Médicas-
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