Please use this identifier to cite or link to this item: https://repositorio.uca.edu.ar/handle/123456789/8738
Título : TRPC3 channels play a critical role in the theta component of pilocarpine-induced status epilepticus in mice
Autor : Phelan, Kevin D. 
Shwe, U Thaung 
Cozart, Michael A. 
Wu, Hong 
Mock, Matthew M. 
Abramowitz, Joel 
Birnbaumer, Lutz 
Zheng, Fang 
Palabras clave : ELECTROENCEFALOGRAFIANEURONASANALISIS ESPECTRALSISTEMA NERVIOSOMEDICAMENTOSEPILEPSIA
Fecha de publicación : 2017
Editorial : Wiley
Cita : Phelan KD, Shwe UT, Cozart MA, et al. TRPC3 channels play a critical role in the theta component of pilocarpine-induced status epilepticus in mice [en línea]. Epilepsia. 2017;58(2):247-254. doi:10.1111/epi.13648 Disponible en: https://repositorio.uca.edu.ar/handle/123456789/8738
Resumen : Abstract: Canonical transient receptor potential (TRPC) channels constitute a family of cation channels that exhibit a regional and cell-specific expression pattern throughout the brain. It has been reported previously that TRPC3 channels are effectors of the brain-derived neurotrophic factor (BDNF)/trkB signaling pathway. Given the long postulated role of BDNF in epileptogenesis, TRPC3 channels may be a critical component in the underlying pathophysiology of seizure and epilepsy. In this study, we investigated the precise role of TRPC3 channels in pilocarpine-induced status epilepticus (SE).
URI : https://repositorio.uca.edu.ar/handle/123456789/8738
ISSN : 0013-9580
1528-1167 (online)
Disciplina: MEDICINA
DOI: 10.1111/epi.13648
Derechos: Acceso Abierto
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