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Título : | Thermodynamics of a model for RNA folding | Autor : | Dell'Erba, Matías G. Zemba, Guillermo Raúl |
Palabras clave : | MOLECULAS DE ARN; PROPIEDADES TERMODINAMICAS; BIOLOGIA; DIAGRAMA DE FEYNMAN; Vernizzi, Graziano; Zee, Anthony; Orland, Henri | Fecha de publicación : | 2009 | Editorial : | American Institute of Physics | Cita : | Dell'Erba MG, Zemba GR. Thermodynamics of a model for RNA folding [en línea]. Physical review E. 2009, E 79 (011913). doi: 10.1103/PhysRevE.79.011913. Disponible en: https://repositorio.uca.edu.ar/handle/123456789/18411 | Resumen : | Abstract: We analyze the thermodynamic properties of a simplified model for folded RNA molecules recently studied by G. Vernizzi, H. Orland, A. Zee (in Phys. Rev. Lett. 94 (2005) 168103). The model consists of a chain of one-flavor base molecules with a flexible backbone and all possible pairing interactions equally allowed. The spatial pseudoknot structure of the model can be effi- ciently studied by introducing a N × N hermitian random matrix model at each chain site, and associating Feynman diagrams of these models to spatial configurations of the molecules. We obtain an exact expression for the topo- logical expansion of the partition function of the system. We calculate exact and asymptotic expressions for the free energy, specific heat, entanglement and chemical potential and study their behavior as a function of temperature. Our results are consistent with the interpretation of 1/N as being a measure of the concentration of Mg++ in solution. | URI : | https://repositorio.uca.edu.ar/handle/123456789/18411 | ISSN : | 2470-0045 (impreso) 2470-0053 (online) |
Disciplina: | INGENIERIA | DOI: | 10.1103/PhysRevE.79.011913 | Derechos: | Atribución-NoComercial-CompartirIgual 4.0 Internacional |
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