Please use this identifier to cite or link to this item: https://repositorio.uca.edu.ar/handle/123456789/18344
Título: Autism spectrum disorder patients may be susceptible to COVID-19 disease due to deficiency in melatonin
Autor: Brown, Gregory M. 
Karthikeyan, Ramanujam 
Pandi Perumal, Seithikurippu R. 
Cardinali, Daniel Pedro 
Palabras clave: TRASTORNO DEL ESPECTRO AUTISTACOVID-19SARS-CoV-2MELATONINA
Fecha de publicación: 2021
Editorial: Elsevier
Cita: Brown, G. M. et al. Autism spectrum disorder patients may be susceptible to COVID-19 disease due to deficiency in melatonin [en línea]. Medical Hypotheses. 2021, 149 . doi: 10.1016/j.mehy.2021.110544. Disponible en: https://repositorio.uca.edu.ar/handle/123456789/18344
Resumen: Abstract: Patients with Autism Spectrum Disorder (ASD) may be particularly prone to develop COVID-19. An unusual extended course of COVID-19 disease illness has been reported in one ASD patient and a group of patients have COVID-19 disease in a neurodevelopmental facility. It has been widely reported that many of those with ASD have substantial sleep disorders with low levels of melatonin and various genetic alterations related to melatonin production have been found. Several lines of evidence point to a substantial role of melatonin in the body’s innate defense system including acting as a scavenger, an antioxidant and modulating the immune system. We therefore hypothesize that melatonin deficiency may predispose those ASD patients who have low melatonin output to COVID-19 disease. Potential implications for treatment are discussed.
URI: https://repositorio.uca.edu.ar/handle/123456789/18344
ISSN: 0306-9877
Disciplina: MEDICINA
DOI: 10.1016/j.mehy.2021.110544
Derechos: Acceso abierto
Fuente: Medical Hypotheses. 2021, 149
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