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Título : Cardiovascular autonomic adaptation to long-term confinement during a 105-day simulated Mars mission
Autor : Wan, Li 
Ogrinz, Barbara 
Vigo, Daniel Eduardo 
Bersenev, Evgeny 
Tuerlinckx, Francis 
Van den Bergh, Omer 
Aubert, André E. 
Fecha de publicación : 2011
Editorial : Aerospace Medical Association
Cita : Wan, L., et al. Cardiovascular autonomic adaptation to long-term confinement during a 105-day simulated Mars mission [en línea]. Postprint de artículo publicado en Aviation, space, and environmental medicine. 2011, 82 (6). doi:10.3357/ASEM.2986.2011. Disponible en:
Resumen : Abstract: Long-term confinement and microgravity may entail alteration in the regulation of the cardiovascular system. A 105-d pilot study of a Mars mission simulation was conducted to test the cardiovascular response to slow-paced breathing and mental stress. Methods: Finger blood pressure and beat-to-beat heart rate were monitored in six male volunteers taking part in a 105-d Mars mission simulation. Data were collected before, during (Days 35-38, 70-72, and 100), and after confinement. Recordings were performed in the sitting position during 5-min spontaneous breathing, 3-min 12 cycle/min breathing, 3-min 6 cycle/min breathing, and 5-min mental task performance. Results: We found significant U-shaped changes across the confinement period in systolic arterial pressure (SAP), diastolic arterial pressure (DAP), and mean arterial pressure (MAP). In the fi rst month of confinement, mental task performance significantly lowered SAP by 34.23 mmHg and MAP by 19.89 mmHg compared to spontaneous breathing, whereas these changes were reversed during other periods. Furthermore, no differences in arterial pressure and heart rate were found between spontaneous, 12 cycle/min, and 6 cycle/min breathing. Conclusions: Our fi ndings are in line with and extend previous fi ndings on the alteration of blood pressure regulation due to longterm confinement.
ISSN : 0095-6562 (impreso)
1943-4448 (online)
Disciplina: MEDICINA
DOI: 10.3357/ASEM.2986.2011
Derechos: Acceso Abierto
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