Please use this identifier to cite or link to this item: https://repositorio.uca.edu.ar/handle/123456789/1637
Título : Heart rate nonlinear dynamics during sudden hypoxia at 8,230 m simulated altitude
Autor : Vigo, Daniel Eduardo 
Pérez Lloret, Santiago 
Videla, Alejandro J. 
Pérez Chada, Daniel 
Hünicken, Horacio M. 
Mercuri, Jorge 
Romero, Ramón 
Nicola Siri, Leonardo C. 
Cardinali, Daniel Pedro 
Palabras clave : SISTEMA NERVIOSO AUTONOMOFRECUENCIA CARDIACAHIPOXIAALTITUDESTUDIO DE CASOS
Fecha de publicación : 2010
Editorial : Elsevier
Cita : Vigo, D. E., et al. Heart rate nonlinear dynamics during sudden hypoxia at 8230 m simulated altitude [en línea]. Wilderness & Environmental Medicine. 2010, 21 (1). doi:10.1016/j.wem.2009.12.022. Disponible en: https://repositorio.uca.edu.ar/handle/123456789/1637
Resumen : Abstract: Acute hypobaric hypoxia is associated with autonomic changes that bring a global reduction of linear heart rate variability (HRV). Although changes in nonlinear HRV can be associated with physiological stress and are relevant predictors of fatal arrhythmias in ischemic heart disease, to what extent these components vary in sudden hypobaric hypoxia is not known. Methods: Twelve military pilots were supplemented with increasing concentrations of oxygen during decompression to 8,230 m in a hypobaric chamber. Linear and nonlinear HRV was evaluated at 8,230 m altitude before, during and after oxygen flow deprivation. Linear HRV was assessed through traditional time- and frequency- domain analysis. Nonlinear HRV was quantified through the short term fractal correlation exponent alpha (αs) and the Sample Entropy index (SampEn). Results: Hypoxia was related to a decrease in linear heart rate variability indexes at all frequency levels. A non significant decrease in αs (basal: 1.39 ± 0.07, hypoxia: 1.11 ± 0.13, recovery: 1.41 ± 0.05, p = 0.054) and a significant increase in SampEn (basal: 1.07 ± 0.11, hypoxia: 1.45 ± 0.12, recovery: 1.43 ± 0.09, p = 0.018) were detected. Conclusions: The observed pattern of diminished linear heart rate variability and increased nonlinear heart rate variability is similar to that seen in subjects undergoing heavy exercise or in patients with ischemic heart disease and high risk for ventricular fibrillation.
URI : https://repositorio.uca.edu.ar/handle/123456789/1637
Disciplina: MEDICINA
DOI: 10.1016/j.wem.2009.12.022
Derechos: Acceso Abierto
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