Por favor, use este identificador para citar o enlazar este ítem: https://repositorio.uca.edu.ar/handle/123456789/12860
Título : How much time is needed in clinical practice to reach a diagnosis of clinically established Parkinson’s disease?
Autor : Rossi, Malco Damián 
Pérez Lloret, Santiago 
Merello, Marcelo 
Palabras clave : ENFERMEDAD DE PARKINSONDIAGNOSTICO MÉDICOMEDICINA CLINICATRASTORNOS DEL MOVIMIENTOTRATAMIENTO FARMACOLOGICO
Fecha de publicación : 2021
Editorial : Elsevier
Cita : Rossi, M. D., Pérez Lloret, S., Merello, M. How much time is needed in clinical practice to reach a diagnosis of clinically established Parkinson’s disease? [en línea]. Parkinsonism & Related Disorders. 2021, 92. doi:10.1016/j.parkreldis.2021.10.016. Disponible en: https://repositorio.uca.edu.ar/handle/123456789/12860
Resumen : Introduction: The implementation of accepted clinical diagnostic criteria has improved the accuracy of a clinical diagnosis of Parkinson’s disease (PD). Time frames of 3 to 10 years have been empirically proposed to reach a diagnosis of clinically established PD. Methods: We explored the time to a Final Clinical Diagnosis (FCD) and the factors that predict faster diagnoses in patients presenting with parkinsonism and/or tremor between 2009 and 2015 at our tertiary center. All patients underwent a standardized workout process to reach a FCD, which included an acute levodopa challenge (LDC) after the first visit. Results: Among the 326 patients included, 215 (66%) received a FCD within the first six months after the LDC. A FCD was reached in 95% and 100% of patients in 33 and 108 months, respectively. PD was the FCD in 196 patients (60.1%). The FCD was reached faster in patients with a positive response to levodopa and when the FCD was PD. Conclusion: The time needed to reach a final diagnosis in the clinical setting was 2.75 years in 95% of patients presenting initially with parkinsonism and/or tremor. Patients with positive responses to levodopa at the LDC, benefited from shorter delays until the FCD.
URI : https://repositorio.uca.edu.ar/handle/123456789/12860
ISSN : 1353-8020 (impreso)
Disciplina: MEDICINA
DOI: 10.1016/j.parkreldis.2021.10.016
Derechos: Acceso abierto. 12 meses de embargo
Aparece en las colecciones: Artículos

Ficheros en este ítem:
Fichero Descripción Tamaño Formato
how-much-time-needed.pdf482,85 kBAdobe PDFVista previa
Visualizar/Abrir
Mostrar el registro Dublin Core completo del ítem

Visualizaciones de página(s)

96
comprobado en 28-mar-2024

Descarga(s)

114
comprobado en 28-mar-2024

Google ScholarTM

Consultar


Altmetric


Este ítem está sujeto a una licencia Creative Commons Licencia Creative Commons Creative Commons