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Campo DC | Valor | Lengua/Idioma |
---|---|---|
dc.contributor.author | Rossi, Malco Damián | es |
dc.contributor.author | Pérez Lloret, Santiago | es |
dc.contributor.author | Merello, Marcelo | es |
dc.date.accessioned | 2021-11-11T19:06:10Z | - |
dc.date.available | 2021-11-11T19:06:10Z | - |
dc.date.issued | 2021 | - |
dc.identifier.citation | Rossi, M. D., Pérez Lloret, S., Merello, M. How much time is needed in clinical practice to reach a diagnosis of clinically established Parkinson’s disease? [en línea]. Parkinsonism & Related Disorders. 2021, 92. doi:10.1016/j.parkreldis.2021.10.016. Disponible en: https://repositorio.uca.edu.ar/handle/123456789/12860 | es |
dc.identifier.issn | 1353-8020 (impreso) | - |
dc.identifier.uri | https://repositorio.uca.edu.ar/handle/123456789/12860 | - |
dc.description.abstract | Introduction: The implementation of accepted clinical diagnostic criteria has improved the accuracy of a clinical diagnosis of Parkinson’s disease (PD). Time frames of 3 to 10 years have been empirically proposed to reach a diagnosis of clinically established PD. Methods: We explored the time to a Final Clinical Diagnosis (FCD) and the factors that predict faster diagnoses in patients presenting with parkinsonism and/or tremor between 2009 and 2015 at our tertiary center. All patients underwent a standardized workout process to reach a FCD, which included an acute levodopa challenge (LDC) after the first visit. Results: Among the 326 patients included, 215 (66%) received a FCD within the first six months after the LDC. A FCD was reached in 95% and 100% of patients in 33 and 108 months, respectively. PD was the FCD in 196 patients (60.1%). The FCD was reached faster in patients with a positive response to levodopa and when the FCD was PD. Conclusion: The time needed to reach a final diagnosis in the clinical setting was 2.75 years in 95% of patients presenting initially with parkinsonism and/or tremor. Patients with positive responses to levodopa at the LDC, benefited from shorter delays until the FCD. | es |
dc.format | application/pdf | es |
dc.language.iso | eng | es |
dc.publisher | Elsevier | es |
dc.rights | Acceso abierto. 12 meses de embargo | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-sa/4.0/ | * |
dc.source | Parkinsonism & Related Disorders. 2021, 92. doi:10.1016/j.parkreldis.2021.10.016 | es |
dc.subject | ENFERMEDAD DE PARKINSON | es |
dc.subject | DIAGNOSTICO MÉDICO | es |
dc.subject | MEDICINA CLINICA | es |
dc.subject | TRASTORNOS DEL MOVIMIENTO | es |
dc.subject | TRATAMIENTO FARMACOLOGICO | es |
dc.title | How much time is needed in clinical practice to reach a diagnosis of clinically established Parkinson’s disease? | es |
dc.type | Artículo | es |
dc.identifier.doi | 10.1016/j.parkreldis.2021.10.016 | - |
dc.identifier.pmid | 34695656 | - |
uca.disciplina | MEDICINA | es |
uca.issnrd | 1 | es |
uca.affiliation | Fil: Rossi, Malco Damián. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia. Departamento de Neurociencias. Sección de Movimientos Anormales; Argentina | es |
uca.affiliation | Fil: Rossi, Malco Damián. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina | es |
uca.affiliation | Fil: Pérez Lloret, Santiago. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina | es |
uca.affiliation | Fil: Pérez Lloret, Santiago. Pontificia Universidad Católica Argentina. Facultad de Ciencias Médicas; Argentina | es |
uca.affiliation | Fil: Pérez Lloret, Santiago. Universidad Abierta Interamericana. Centro de Altos Estudios en Ciencias Humanas y de la Salud; Argentina | es |
uca.affiliation | Fil: Pérez Lloret, Santiago. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Fisiología; Argentina | es |
uca.affiliation | Fil: Merello, Marcelo. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia. Departamento de Neurociencias. Sección de Movimientos Anormales; Argentina | es |
uca.affiliation | Fil: Merello, Marcelo. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina | es |
uca.affiliation | Fil: Merello, Marcelo. Pontificia Universidad Católica Argentina. Facultad de Ciencias Médicas; Argentina | es |
uca.version | publishedVersion | es |
item.grantfulltext | open | - |
item.fulltext | With Fulltext | - |
item.languageiso639-1 | en | - |
crisitem.author.dept | Laboratorio de Neurobiología Molecular | - |
crisitem.author.dept | Consejo Nacional de Investigaciones Científicas y Técnicas | - |
crisitem.author.orcid | 0000-0003-3383-8566 | - |
crisitem.author.orcid | 0000-0001-9069-6512 | - |
crisitem.author.parentorg | Instituto de Investigaciones Biomédicas - BIOMED | - |
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