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https://repositorio.uca.edu.ar/handle/123456789/22029| Título: | Histamine H3 receptor: an emerging target for cancer therapy? | Autor: | Lauretta, Paolo Martínez Vivot, Rocío Velazco, Águeda Medina, Vanina Alejandra |
Palabras clave: | HISTAMINA; RECEPTORES DE HISTAMINA; ONCOLOGIA MOLECULAR; CANCER | Fecha de publicación: | 2025 | Editorial: | Springer | Resumen: | Achieving better clinical outcomes in cancer research requires a deeper understanding of tumoral biology and the application of this knowledge within a clinic setting. The aim of this review is to briefly summarize the current knowledge on H3R molecular pharmacology, the clinical use of H3R antagonists, and the most recent findings reporting H3R role in cancer biology. We will discuss in detail the current landscape and clinical perspectives of the modulation of this H3R on cancer progression and treatment. We propose H3R as a promising molecular target for cancer drug repurposing and development. | URI: | https://repositorio.uca.edu.ar/handle/123456789/22029 | ISSN: | 1023-3830 | DOI: | 10.1007/s00011-025-02054-z | Derechos: | Atribución-NoComercial-CompartirIgual 4.0 Internacional | Fuente: | Inflammation Research, vol. 74 |
| Appears in Collections: | Artículos |
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