Please use this identifier to cite or link to this item: https://repositorio.uca.edu.ar/handle/123456789/10355
Título : High doses of melatonin as a potential therapeutic tool for the neurologic sequels of covid-19 infection
Autor : Cardinali, Daniel Pedro 
Palabras clave : MELATONINACORONAVIRUSCOVID-19ACCIDENTE CEREBROVASCULARNEUROPROTECCIONNEUROLOGIA
Fecha de publicación : 2020
Editorial : ST Bio-Life
Cita : Cardinali, D.P. High doses of melatonin as a potential therapeutic tool for the neurologic sequels of covid-19 infection [en línea]. Melatonin Research. 2020, 3(3). doi:10.32794/11250064 Disponible en: https://repositorio.uca.edu.ar/handle/123456789/10355
Resumen : Abstract: The therapeutic potential of melatonin as an agent to counteract the consequences of COVID-19 infections is due to its wide-ranging effects as a powerful antioxidant, anti-inflammatory, and immunostimulant, as well as to a possible antiviral action. In view of the recently reported evidence on the occurrence of neurological sequels in COVID-19-infected patients, another putative application of melatonin emerges based on its neuroprotective properties. In this manuscript a brief discussion of melatonin activity in animal models of ischemic and hemorrhagic stroke and the allometric calculations of the possible human equivalent doses are made. Based on the safety of melatonin, and in order to maximize its therapeutic opportunity, doses of 100 - 300 mg p.o. or i.v. are proposed.
URI : https://repositorio.uca.edu.ar/handle/123456789/10355
ISSN : 2641-0281
Disciplina: MEDICINA
DOI: 10.32794/11250064
Derechos: Acceso abierto
Appears in Collections:Artículos

Files in This Item:
File Description SizeFormat
high-doses-melatonin-potential.pdf213,18 kBAdobe PDFThumbnail
View/Open
Show full item record

Page view(s)

145
checked on Oct 24, 2020

Download(s)

56
checked on Oct 24, 2020

Google ScholarTM

Check


Altmetric


This item is licensed under a Creative Commons License Creative Commons