Please use this identifier to cite or link to this item: https://repositorio.uca.edu.ar/handle/123456789/1654
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dc.contributor.authorPérez Lloret, Santiagoes
dc.contributor.authorRossi, Malco Damiánes
dc.contributor.authorMerello, Marceloes
dc.contributor.authorRascol, Olivieres
dc.contributor.authorCardinali, Daniel Pedroes
dc.date.accessioned2019-05-02T14:01:17Z-
dc.date.available2019-05-02T14:01:17Z-
dc.date.issued2011-
dc.identifier.citationPérez Lloret, S., et al. Non-motor symptoms group in Parkinson's disease patients : results of a pilot, exploratory study [en línea]. Parkinson's Disease. 2011. doi:10.4061/2011/473579. Disponible en: https://repositorio.uca.edu.ar/handle/123456789/1654es
dc.identifier.issn2090-8083 (impreso)-
dc.identifier.issn2042-0080 (online)-
dc.identifier.urihttps://repositorio.uca.edu.ar/handle/123456789/1654-
dc.description.abstractAbstract: Nonmotor symptoms (NMS) like neuropsychiatric symptoms, sleep disturbances or autonomic symptoms are a common feature of Parkinson’s disease (PD). To explore the existence of groups of NMS and to relate them to PD characteristics, 71 idiopathic non-demented PD out-patients were recruited. Sleep was evaluated by the PD Sleep Scale (PDSS). Several neuropsychiatric, gastrointestinal and urogenital symptoms were obtained from the NMSQuest. Sialorrhea or dysphagia severity was obtained from the Unified PD Rating Scale activities of daily living section. MADRS depression scale was also administered. Exploratory factor analysis revealed the presence of 5 factors, explaining 70% of variance. The first factor included PDSS measurement of sleep quality, nocturnal restlessness, off-related problems and daytime somnolence; the second factor included nocturia (PDSS) and nocturnal activity; the third one included gastrointestinal and genitourinary symptoms; the forth one included nocturnal psychosis (PDSS), sialorrhea and dysphagia (UPDRS); and the last one included the MADRS score as well as neuropsychiatric symptoms. Sleep disorders correlated with presence of wearing-off, nocturia with age >69 years, and nocturnal psychosis with levodopa equivalent dose or UPDRS II score. Neuropsychiatric symptoms correlated with UPDRS II+III score and non-tricyclic antidepressants. These results support the occurrence of significant NMS grouping in PD patients.es
dc.formatapplication/pdfes
dc.languageenges
dc.language.isoenges
dc.publisherHindawies
dc.relation.ispartofseriesParkinson’s Disease;Volume 2011-
dc.rightsAcceso Abiertoes
dc.rights.urihttps://creativecommons.org/licenses/by-nc-sa/4.0/es
dc.sourceParkinson's Disease. 2011es
dc.subjectENFERMEDAD DE PARKINSONes
dc.subjectSINTOMAS NO MOTORESes
dc.subjectTRATAMIENTO FARMACOLOGICOes
dc.subjectENFERMEDADES NEUROGENERATIVASes
dc.titleNon-motor symptoms groups in Parkinson's disease patients : results of a pilot, exploratory studyes
dc.typeArtículoes
dc.identifier.doi10.4061/2011/473579-
uca.pathFacultad de Ciencias Médicas|Departamento de Docencia e Investigaciónes
uca.disciplinaMEDICINAes
uca.filename/home/data-uca-generic/folder_generic/IIBiomedicas/non-motor-symptoms-groups-parkinson/metadata.xmles
uca.issnrd1es
uca.affiliationFil: Pérez Lloret, Santiago. Hospital y Universidad Paul Sabatier. Departamento de Farmacología Clínica y Neurociencias; Franciaes
uca.affiliationFil: Pérez Lloret, Santiago. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia. Insitituto de Invesitgaciones Neurológícas Raul Carrera. Sección de Desórdenes del Movimiento; Argentinaes
uca.affiliationFil: Rossi, Malco. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia. Insitituto de Invesitgaciones Neurológícas Raul Carrera. Sección de Desórdenes del Movimiento; Argentinaes
uca.affiliationFil: Merello, Marcelo. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia. Insitituto de Invesitgaciones Neurológícas Raul Carrera. Sección de Desórdenes del Movimiento; Argentinaes
uca.affiliationFil: Rascol, Olivier. Hospital y Universidad Paul Sabatier. Departamento de Farmacología Clínica y Neurociencias; Franciaes
uca.affiliationFil: Cardinali, Daniel P. Pontificia Universidad Católica Argentina. Facultad de Ciencias Médicas. Departamento de Docencia e Investigación; Argentinaes
uca.affiliationFil: Cardinali, Daniel P. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Fisiología; Argentinaes
uca.versionpublishedVersiones
item.languageiso639-1en-
item.grantfulltextopen-
item.fulltextWith Fulltext-
crisitem.author.deptLaboratorio de Neurobiología Molecular-
crisitem.author.deptConsejo Nacional de Investigaciones Científicas y Técnicas-
crisitem.author.deptConsejo Nacional de Investigaciones Científicas y Técnicas-
crisitem.author.deptInstituto de Investigaciones Biomédicas - BIOMED-
crisitem.author.orcid0000-0001-9069-6512-
crisitem.author.orcid0000-0003-3383-8566-
crisitem.author.orcid0000-0002-0813-9088-
crisitem.author.parentorgInstituto de Investigaciones Biomédicas - BIOMED-
crisitem.author.parentorgFacultad de Ciencias Médicas-
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